Cartia XT® (Diltiazem HCl Extended-Release Capsules, USP)
Tiazac mg, purple, capsule. Subsequent dosage adjustments should be based on clinical response. Patients with hypertension or heart failure should be advised to only use hawthorn with their prescribed medications after discussion with their prescriber, cartia xt. Moderate The combination of diltiazem and a beta-blocker, like bisoprolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Moderate High doses of fish oil supplements may produce a blood pressure lowering effect. Worsened psychosis has been reported with the combination of diltiazem and lithium. This effect is of particular concern in the setting of acute myocardial infarction, unstable angina, or other acute hemodynamic compromise. Do not start, stop, or change the dose cartia any drug without checking with your doctor. Ginger, Zingiber officinale: Diltiazem can inhibit the metabolism of CYP isoenzymes, including those that are responsible for the metabolism of escitalopram. Moderate CYP enzyme inhibitors, like diltiazem, may inhibit the hydroxylation of doxercalciferol, thereby decreasing the formation of the active metabolite and thus, cartia efficacy. If diltiazem is discontinued, oxycodone plasma concentrations will decrease resulting in reduced efficacy of the opioid and potential withdrawal syndrome in a patient who has developed physical dependence to oxycodone. Diltiazem ER works by relaxing blood vessels, which in turn allows the heart to not have to pump as hard. Dose adjustments of calcium-channel blockers may be necessary. Ribociclib; Letrozole:
Minor Additive bradycardia may caria in patients receiving paclitaxel and other drugs known to cause bradycardia, such as calcium-channel blockers like diltiazem. Moderate The combination of diltiazem and a beta-blocker, like bisoprolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. If the antihypertensive cannot be stopped for 24 hours before chemotherapy doses of amifostine, patients should not receive amifostine. This is not a complete list of the side effects associated with diltiazem. Moderate Calcium channel blockers may potentiate the hypotension seen with aldesleukin, IL 2. You can also report them cadtia the U. Patients being given lofexidine in an outpatient setting should be capable of and instructed on self-monitoring for hypotension, orthostasis, bradycardia, and associated symptoms. Amlodipine; Telmisartan: And it always seems that my pulse rate is low when I take my pressure with the machine. Isoniazid, INH; Rifampin: It has not been determined whether other drugs which inhibit CYP3A4 hepatic enzymes, like dilitiazem, would have a similar effect. Available for Android and iOS devices. More study is needed regarding ginkgo's effects on CYP3A4 and whether clinically significant drug interactions result. Moderate Alemtuzumab may cause hypotension. Cartia cardiovascular cartia e. Chlophedianol; Guaifenesin; Phenylephrine: Avoiding calcium channel blockers by using other classes of antihypertensive agents that are not substrates for CYP3A4 may be appropriate in some cartia requiring long-term administration of inhibitory drugs. Major Diltiazem has been shown to increase encainide AUC and half-life. Aspirin, ASA; Oxycodone:
Lumacaftor is a strong CYP3A inducer. Systemic drug interactions with the urethral suppository MUSE or alprostadil intracavernous injection are unlikely in most patients because low or undetectable amounts of the drug are found in the csrtia venous circulation following administration. Dapagliflozin; Saxagliptin: Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. Major Coadministration of atazanavir with diltiazem may result in increased plasma concentrations of either drug. If you think there cartia been an overdose, call your poison control center or get medical care right away, cartia xt. If coadministration cartia necessary, monitor patients closely at frequent intervals and consider a dosage reduction of codeine until stable drug effects are achieved. Diltiazem should not be used in advanced aortic stenosis because it can cause a worsening of the abnormal pressure gradient associated with cartia condition. Visually inspect parenteral products for particulate matter and discoloration prior to ct whenever solution and container permit. Heart Failure amlodipinelisinoprilfurosemidecarvedilolmetoprololdiltiazemspironolactoneLasixMore Initially, 30 mg PO 4 times per day administered before meals and at bedtime, gradually increasing the dosage at 1- or 2-day intervals until angina is optimally controlled. Discard any unused portion of diltiazem after vial entry. Refer to our editorial policy for content sources and attributions. Clinical practice guidelines recommend caartia nondihydropyridine calcium channel blocker to slow the ventricular heart rate in patients with paroxysmal, persistent, or permanent atrial fibrillation. Brompheniramine; Carbetapentane; Phenylephrine: Major Avoid the concomitant use of midostaurin and diltiazem as significantly increased exposure of midostaurin and its active metabolites may occur resulting in increased toxicity.
Inject dose IV over 2 minutes. If diltiazem is discontinued, consider increasing the oxycodone dose until stable drug effects are achieved and caria for evidence of opioid withdrawal. Moderate Diltiazem is a CYP3A4 inhibitor and may reduce the metabolism of clorazepate and increase the potential for benzodiazepine toxicity. Swelling of the legs can add weight to the body. Cartia Ibuprofen: This is not a list of all xh or health problems that interact with Cartia XT diltiazem long-acting capsules. Guaifenesin; Hydrocodone; Pseudoephedrine: Diltiazem 30 mg-MYL, white, round, film coated. All rights reserved. Skip to Content. Estradiol; Norgestimate: These are not all of the side effects that may occur. The interaction is presumed due to increased simvastatin bioavailability cartia inhibition of CYP3A4 metabolism by diltiazem. Diltiazem ER, in most situations, should be swallowed whole and not chewed or crushed. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. All drugs may cause side effects. The metabolism of progesterone is inhibited by ketoconazole, cartia xt, a known acrtia of cytochrome P 3A4 hepatic enzymes. In addition, diltiazem inhibits CYP3A4, a partial pathway for propafenone metabolism. Major The cardiovascular effects of sympathomimetics, such as ephedrine, may reduce the antihypertensive effects produced by calcium-channel blockers. Studies that were done have concluded that diltiazem does not have any significant effect on lowering blood sugar. Caution and close monitoring are advised if these drugs are used together. Neuromuscular blockers: Monitor blood pressure if the combination is necessary. Acetaminophen; Oxycodone: To find out if your medication is available as a Teva generic, contact your local pharmacy.
Print this page Add to My Med List. Both ivabradine and diltiazem may cause bradycardia. Amphetamine; Dextroamphetamine Salts: Alternatively, general anesthetics can potentiate the cartis effects of calcium-channel blockers, cartia xt. According to the manufacturer of conivaptan, subsequent treatment with CYP3A substrates may be initiated no sooner than 1 week after completion of conivaptan therapy. Major Avoid carita of olaparib with cartia and consider alternative agents with less CYP3A4 inhibition due to increased olaparib exposure. Major Use caution if coadministration of dronabinol with diltiazem is necessary, and monitor for an increase in dronabinol-related adverse reactions e. Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Coadministration may increase the exposure of both drugs. Codeine; Promethazine: Do not start, stop, or change the dose of any drug without checking with your doctor. Moderate Be alert for symptoms of ergot toxicity cartla using methylergonovine and diltiazem together is medically necessary. The amount of swelling was not indicated by the drug manufacturer. Elevated pimozide concentrations occurring through inhibition of CYP3A4 cartla lead to QT prolongation, ventricular arrhythmias, and sudden death. Carbetapentane; Guaifenesin; Phenylephrine: BasicDescription Back to Top. Inhibition of methadone metabolism can lead to toxicity including CNS adverse effects and potential for QT prolongation and torsades de pointes when high doses of methadone are used e. We comply with the HONcode standard for trustworthy health information - verify here. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Moderate Colesevelam may decrease the cwrtia of diltiazem. Minor Nevirapine is an inducer of the cytochrome PA enzyme. Regards, Derek Dore, PharmD. Patients with hepatic disease, such as cirrhosis or hepatic failure, can experience a delayed clearance of diltiazem and can be at greater risk for accumulation and toxicity. The dosages and indications for these agents are not identical. Major Concomitant use of bretylium with other antiarrhythmis, such zt diltiazem, cagtia have additive, antagonistic, or synergistic electrophysiologic, pharmacodynamic, or toxic effects, including hypotension.
Refer to our editorial policy for content sources and attributions. If treatment with diltiazem is unavoidable, lomitapide should be stopped during the course of treatment. Moderate Local anesthetics may cause additive hypotension in combination with antihypertensive agents. A dosage regimen cartia 30 mg PO 3 times daily, titrated to 60 to 90 mg PO 3 times daily, has been studied. Monitor blood pressure if the combination is necessary. Estradiol; Levonorgestrel: If diltiazem is discontinued, fentanyl plasma concentrations will decrease resulting in reduced efficacy of the opioid and potential withdrawal syndrome in a patient who has developed physical dependence to fentanyl. Ginkgo, Ginkgo biloba: Call your doctor for medical advice about side effects. Although leading drug interaction texts differ in the potential for an interaction between diethylpropion and this group of antihypertensive agents, these effects are likely to be clinically significant and have been described cartia hypertensive patients on these medications, cartia xt. Dolutegravir; Rilpivirine: Complete AV block resulting in a nodal rhythm and sinus bradycardia resulting in hospitalization and pacemaker insertion have been reported during combination therapy of clonidine with diltiazem or verapamil. In patients with hypertension receiving a concurrent CYP3A4 inhibitor, initiate eplerenone at 25 mg PO once daily; the dose may be increased to a maximum of 25 mg PO twice daily for inadequate blood pressure response. Isoniazid, INH; Rifampin: Concomitant use of diltiazem, a CYP3A4 inhibitor, and dihydroergotamine, a CYP3A4 substrate with a cartia therapeutic range, may result in increased ergot alkaloid levels. Administered once-daily. In addition, calcium channel blockers may cause peripheral edema and clinically significant constipation; some agents may cause generalized aching, headache, and muscle pain. Periodic evaluation of blood pressure is advisable during concurrent use of methylphenidate and antihypertensive agents, particularly during initial coadministration and after dosage increases of methylphenidate. In geriatric vs. Ethinyl Estradiol; Ethynodiol Diacetate: Explore Apps.
Avoid use in patients with left ventricular systolic dysfunction or decompensated heart failure. Dolutegravir; Rilpivirine: Dihydrocodeine; Guaifenesin; Pseudoephedrine: If diltiazem is discontinued, oxycodone plasma concentrations will decrease resulting in reduced efficacy of the opioid and potential withdrawal syndrome in a patient who has developed physical dependence to oxycodone. Cartia any unused portion of diltiazem after vial entry. Refer to our editorial policy for content sources and attributions. Dextromethorphan; Quinidine: Acetaminophen; Butalbital; Caffeine; Codeine: Call your doctor for medical advice about side effects. If use together is necessary, obtain an ECG prior to lacosamide initiation and after treatment has been titrated to steady-state. Specific dosage adjustment recommendations are available cartia the Colcrys product for patients who have taken diltiazem in the past 14 days or require concurrent use: Moderate Consider a reduced dose of alfentanil with frequent monitoring for respiratory depression and sedation if concurrent use of diltiazem is necessary. You may also report side effects at http: Aspirin, cartia xt, ASA; Oxycodone: Diltiazem Cardizem LA is a medication used to treat hypertension high blood pressure and chest pain. Even though it may be rare, some people may have very bad and sometimes deadly cartia effects when taking a drug, cartia xt. Use of diltiazem for treatment of atrial fibrillation or flutter may precipitate severe ventricular arrhythmias and is contraindicated in patients with Wolff-Parkinson-White syndrome or Lown-Ganong-Levine syndrome. Dose adjustments should be made for diltiazem based on clinical response. Thus, for more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Monitor the patient's blood pressure closely when using the compounded formulation. Artemether; Lumefantrine: Amlodipine; Benazepril: If diltiazem is discontinued, consider increasing the alfentanil dose until stable drug effects are achieved and monitor for evidence of opioid withdrawal.
What do I need to tell my doctor BEFORE I take Cartia XT?
Carbinoxamine; Pseudoephedrine: Further, in patients with cardiogenic shock, intravenous diltiazem is contraindicated, cartia xt. See also: Carbinoxamine; Phenylephrine: Diltiazem is an inhibitor of the hepatic isoenzyme CYP3A4; rilpivirine is metabolized by this isoenzyme. Diltiazem is metabolized by CYP3A4. Monitor for loss of diltiazem efficacy and or increased adverse events coming from the topiramate component of phentermine;topiramate. Diltiazem should be taken with a full glass of water either with or without food. Ethinyl Estradiol; Norethindrone: Ethinyl Estradiol; Norgestrel: Additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. It is possible that additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. You may also report side effects at http: Cartia dose adjustment is not advised when coadministered with diltiazem. Dose adjustments of paricalcitol may be required. Dose adjustments should be made for diltiazem based on clinical response. Discontinuation of diltiazem could decrease dihydrocodeine plasma concentrations, decrease opioid efficacy, and potentially lead to a withdrawal syndrome in those with physical dependence to dihydrocodeine. Teva's generic medications are available in most pharmacies across the United States, though not all pharmacies carry the same Teva medications. A heart beat less than 60 beats per minute is defined as bradycardia. Coadministration has been associated with an increased risk of hypotension and shock. Close observation and monitoring of blood glucose is necessary to maintain adequate glycemic control.
What do I need to tell my doctor BEFORE I take Cartia XT?
A nondihydropyridine calcium channel blocker is the preferred agent in patients with chronic obstructive pulmonary disease. Moderate The combination of diltiazem and a beta-blocker, like nebivolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Cardizem CD mg, blue, ,. Read all information given to you. A heart beat less than 60 beats per minute is defined as bradycardia. Lumacaftor is a strong CYP3A inducer. Alfuzosin is primarily metabolized by the CYP3A4 hepatic enzyme. Discard any unused portion of diltiazem after vial entry. Swallow whole; do not split, crush, or chew the tablets; per the labeled instructions to patients, the medication is formulated to slowly release. Esterified Estrogens; Methyltestosterone: Coadministration is contraindicated in patients with renal or hepatic impairment because colchicine accumulation may be greater in these populations. Guaifenesin; Hydrocodone: Prolongation of QT interval, torsades de pointes, and sudden cardiac death have been reported after concomitant administration of cisapride a CYP3A4 substrate with other CYP3A4 inhibitors. Consult with your doctor if you have been experiencing hyperglycemia for proper evaluation. The catalog displays all strengths and sizes along with the description, imprint code, NDC and photo for each product.
Do not start, stop, or change the dose of any drug without checking with your doctor. For patients with breast cancer, neuroendocrine tumors, renal cell carcinoma, and renal angiolipoma with tubular sclerosis complex TSC , reduce the dose of Afinitor to 2. Dextromethorphan; Guaifenesin; Pseudoephedrine: Based on the pharmacology of conivaptan, there is also potential for additive hypotensive effects when coadministered with calcium-channel blockers. This is not a complete list of the side effects associated with diltiazem. The coadministration of eliglustat with both diltiazem and a moderate or strong CYP2D6 inhibitor is contraindicated in all patients. Major Avoid coadministration of diltiazem and apalutamide due to decreased plasma concentrations of diltiazem. Moderate During concurrent use of citalopram and diltiazem, clinicians should monitor patients for a potential increase in side effects or toxicity. Avoid use in patients with pre-excitation, left ventricular systolic dysfunction, or decompensated heart failure. Moderate Consider a reduced dose of fentanyl with frequent monitoring for respiratory depression and sedation if concurrent use of diltiazem is necessary. Ibuprofen; Oxycodone: Caution and close monitoring are advised if these drugs are used together. Moderate Prazosin is well-known to produce a 'first-dose' phenomenon. Diltiazem ER is also used to manage angina chest pain. Major Avoid coadministration of olaparib with diltiazem and consider alternative agents with less CYP3A4 inhibition due to increased olaparib exposure. Clinical practice guidelines for cardiopulmonary resuscitation and emergency cardiovascular care also suggest a nondihydropyridine calcium channel blocker for PSVT if adenosine or vagal maneuvers fail to convert, if PSVT recurs after these therapies, or if these therapies disclose another SVT. It is possible that edema or swelling may occur from taking diltiazem. It should be noted that because citalopram is metabolized by multiple enzyme systems, inhibition of one pathway may not appreciably decrease citalopram clearance. Chlorthalidone; Clonidine: It's possible that edema, or swelling, may occur from taking diltiazem. It is advisable to monitor blood pressure if the combination is necessary. If concurrent treatment with diltiazem is necessary, strongly consider a lapatinib carrtia reduction. Concomitant use of diltiazem, a CYP3A4 inhibitor, and ergotamine, a CYP3A4 substrate with a cartia therapeutic range, may result in increased ergot alkaloid levels. Adjust the dosage based on clinical response. The benefits of the use of lovastatin in patients taking diltiazem cartis be carefully weighed against the risks of this combination. However, as a single mg intravenous dose, fosaprepitant only weakly inhibits CYP3A4 for a duration of 2 days; there is no evidence of CYP3A4 cagtia. Alcohol increases the rate at which some controlled and extended release formulas of diltiazem such as Cardizem CD release diltiazem in vitro. In addition, orthostatic vital signs should be monitored in patients who are at risk for hypotension, cartia as those receiving cariprazine in combination with antihypertensive agents. In addition, the presence of medications in the cartia that attenuate erectile function may influence the response to alprostadil.
Aldesleukin, IL Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine: Acetaminophen; Oxycodone: Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine: Moderate Diltiazem has been reported to increase the plasma level and hypotensive effects of nifedipine via CYP3A4 inhibition. Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy. If concurrent treatment with diltiazem is necessary, strongly consider a lapatinib dose reduction. Coadministration may increase the exposure of both drugs. Moderate Melatonin may impair the efficacy of some calcium-channel blockers, and caution is advised with concurrent use. Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate: Etoposide, VP Ethinyl Estradiol; Norethindrone: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Lansoprazole; Naproxen: Coadministration with diltiazem increased naloxegol exposure by approximately 3. Moderate Monitor for increased eletriptan-related adverse effects if coadministered with diltiazem. Angina Pectoris Prophylaxis aspirinmetoprololatenololdiltiazemnitroglycerinnifedipineisosorbide mononitrateMore Monitor patients closely for alpha-adrenergic effects including hypotension, drowsiness, lethargy, and bradycardia.